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What Is The Life Expectancy With Hereditary Amyloidosis

A MyAmyloidosisTeam Member asked a question 💭
Milton Keynes, UK
August 21
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A MyAmyloidosisTeam Member

Life expectancy with hereditary amyloidosis, specifically hereditary transthyretin (hATTR) amyloidosis, varies based on the specific gene mutation involved. Here are some key points from the knowledge base:

- General Life Expectancy: People with hATTR amyloidosis typically live between seven and 12 years after diagnosis
- Show Full Answer

Life expectancy with hereditary amyloidosis, specifically hereditary transthyretin (hATTR) amyloidosis, varies based on the specific gene mutation involved. Here are some key points from the knowledge base:

- General Life Expectancy: People with hATTR amyloidosis typically live between seven and 12 years after diagnosis.
- Genetic Mutations:
- S50R Mutation: Only 21% of people with this mutation live 10 years or longer after diagnosis.
- V71A Mutation: About 85% of people with this mutation live 10 years or longer after diagnosis.
- V30M Mutation: People with this mutation often respond well to liver transplants, which can improve life expectancy.

Other factors influencing outlook include age, the type of amyloid present, and how much the brain and heart are affected by amyloid deposits.

August 21

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