Amyloidosis is a rare disease characterized by the misfolding of proteins. Normally, proteins fold into precise shapes to perform specific tasks. In amyloidosis, proteins are misfolded and clump together, forming amyloid fibrils or amyloid deposits. These deposits accumulate in various organs, causing damage and potentially Show Full Answer

Amyloidosis is a rare disease characterized by the misfolding of proteins. Normally, proteins fold into precise shapes to perform specific tasks. In amyloidosis, proteins are misfolded and clump together, forming amyloid fibrils or amyloid deposits. These deposits accumulate in various organs, causing damage and potentially leading to organ failure. The condition is underdiagnosed, with about 4,500 people in the U.S. diagnosed each year with AL amyloidosis, the most common type.

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