Thsnk your response. I go to my ATTRwt doctor tomorrow for a 6 month check up. Will ask him what he thinks we should do about the nerve pain. I'll let you know,

Do you see a neurologist? I have peripheral neuropathy due to wt ATTR Amyloidosis. I was taking gabapentin for my nerve damage but it had quit helping. They changed me to Lyrica and it is helping more with the pain. I also use insulin infusions to reverse the neuropathy in my arms, hands, legs and feet.

Thanks for comment on ankle pain. Will talk to Amyloidosis doctor at next appointment.

Quite possible, it may be a deposition of amyloid fibrils around the nerve that affects your ankle. It certainly should be considered as a cause of your pain.

Hi, I have been taking Allopurinol for 20 years now for kidney stones/gout. The pain near my ankle is more recent and affects the nerve that passes right near the ankle bone. Since no one can figure out why I have that pain, I'm beginning to think is has something to do with ATTRwt..