Does A Negative Attr Gene Test Mean I Have Wild Type?
thanks, Sheldon. I was waiting for your answer… Yes, I had a negative AL test so I’m assuming wild type. Continued prayers for everyone.
Genetic testing for hereditary ATTR otherwise known as hATTR or vATTR, that yields a negative result for all 130 genome responsible for hATTR, may mean that you either have wtATTR or AL Amyloidosis. A Kappa/Lamda blood test and a 24-hour urine test for light proteins can rule out AL Amyloidosis. Then you know with certainty that you have wtATTR.
I have biopsy-proven Cardiac AL. Urine has always been negative, as was fat-pad (abdominal) aspirate.
A negative ATTR gene test does not automatically mean you have wild-type ATTR amyloidosis. Here's a detailed explanation:
- Testing Process
- If a protein sequence analysis test on a biopsy sample shows that the TTR protein is involved, a blood sample is sent for a genetic-sequencing test to examine the DNA chains.
- read more
This AI-generated response comes from MyAmyloidosisTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.
love it!!! stay wild
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