Connect with others who understand.

Sign up Log in
Resources
About MyAmyloidosisTeam
Powered By
Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does A Negative Attr Gene Test Mean I Have Wild Type?

A MyAmyloidosisTeam Member asked a question 💭
Sacramento, CA
September 14
View reactions
A MyAmyloidosisTeam Member

thanks, Sheldon. I was waiting for your answer… Yes, I had a negative AL test so I’m assuming wild type. Continued prayers for everyone.

September 14
A MyAmyloidosisTeam Member

Genetic testing for hereditary ATTR otherwise known as hATTR or vATTR, that yields a negative result for all 130 genome responsible for hATTR, may mean that you either have wtATTR or AL Amyloidosis. A Kappa/Lamda blood test and a 24-hour urine test for light proteins can rule out AL Amyloidosis. Then you know with certainty that you have wtATTR.

September 14
A MyAmyloidosisTeam Member

I have biopsy-proven Cardiac AL. Urine has always been negative, as was fat-pad (abdominal) aspirate.

September 23
A MyAmyloidosisTeam Member

A negative ATTR gene test does not automatically mean you have wild-type ATTR amyloidosis. Here's a detailed explanation:

- Testing Process
- If a protein sequence analysis test on a biopsy sample shows that the TTR protein is involved, a blood sample is sent for a genetic-sequencing test to examine the DNA chains.
- read more

A negative ATTR gene test does not automatically mean you have wild-type ATTR amyloidosis. Here's a detailed explanation:

- Testing Process:
- If a protein sequence analysis test on a biopsy sample shows that the TTR protein is involved, a blood sample is sent for a genetic-sequencing test to examine the DNA chains.
- If this genetic-sequencing test produces no identifiable mutations, then wild-type ATTR amyloidosis is the resulting diagnosis.

- Other Tests:
- Doctors may also perform other laboratory tests, including blood or urine tests, to determine whether the organs are working correctly.
- Certain blood tests may be used to track amyloidosis.

In summary, a negative ATTR gene test is a significant step towards diagnosing wild-type ATTR amyloidosis, but additional tests and evaluations are typically required to confirm the diagnosis.

 This AI-generated response comes from MyAmyloidosisTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Wild-Type Amyloidosis — An Overview | MyAmyloidosisTeam
Types of Amyloidosis | MyAmyloidosisTeam
September 14
A MyAmyloidosisTeam Member

love it!!! stay wild

September 23

Related content

View All

Is Wild Type ATTR Affect Life Expectancy More So Than Hereditary ATTR-CM?

A MyAmyloidosisTeam Member asked a question 💭
Walnut Creek, CA

Hello….Those Of You With Hattr. Did It Tend To Run In Your Families? And Was The Age Of Onset Younger Than 75?

A MyAmyloidosisTeam Member asked a question 💭
Sacramento, CA

Is Wild Type And Hereditary Attr Treated With The Same Meds

A MyAmyloidosisTeam Member asked a question 💭
Detroit, MI
Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data Policy and Privacy policies.Your privacy is our priority Lock Icon
Already a Member? Log in