I usually felt great immediately after chemo. But as soon as the steroids would wear off, the typical would start. The nausea and misery would come on strong as the take home prescription of steroids was finished. In my case they were a positive, and had no negative indications.

You should definitely speak with the doctor about it. The worst I had was not being able to sleep for a day or two

I know that steroid Rx can increase agitation and mimic mood swings of bipolar d/o.