There are some studies showing that it can break down beta amyloid, which is Alzheimers Disease. That is an entirely different type of amyloid than AL, ATTR, AA, etc.
CONTRAINDICATIONS
Aspirin: Nattokinase may increase the risk of intracerebral hemorrhage (14).
Anticoagulant/antiplatelet/fibrinolytic drugs: Theoretically, nattokinase may increase the risk of bleeding. In a small study of healthy young men, enhanced fibrinolysis and antithrombosis after a single-dose of oral nattokinase occurred, although effects in this group were deemed to be within normal range (17). Lab studies indicate nattokinase is a heparin-binding protein with a binding affinity of ~250 nM and the interaction is chain-length dependent. It also interfered in heparin interactions with antithrombin and fibroblast growth factors (18).
Warfarin: Nattō is rich in vitamin K. In addition, Bacillus subtilis bacteria in nattō continue synthesizing vitamin K in the intestine following consumption, which can reduce the effects of warfarin (15).

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It is also a supplement which are not regulated by the FDA and can contain just about anything the manufacturer decides to throw in the mix. Since some amyloid patients have Factor X deficiency, it is a good idea to stay away from anything that could further thin your blood. It's best to ALWAYS discuss ANY supplement or over the counter product with your doctor before taking it! You don't want to counteract the medicines they have you on!

Stanford.....you are good man! Thanks for sharing.

All I know of that a healer I work with said that it was not good for me.
Your mileage might vary?

As for me (me):
Amyloidosis is on a certain path to kill me in time.
FOR ME the uncertainty of the potential that nattokinase has if a far greater risk FOR ME than the other option =nothing=

However, I always add prayer to God through Christ who DOES strengthen me.

Most frustrating thing
FOR ME
Is the pain and stress on my wife who has already endured the loss of a previous husband.

Anyway: MY has always been on of facing challenges head on and NOT accepting every "authority" at face value...
ESPECIALLY government and government dependent establishments.

My wife saved my life once while in hispital, and that of her mother another time in hispital BY NOT TAKING AT FACE VALUE but by asking questions and demandubg answers.

Yes LISTEN TO EXPERTS...and other experts and others...compare answers...make your own decisions.

Bottom line FOR ME is that I am dieing anyway, no matter what, si doing SOMETHING is preferable TO ME than curling into figurative fetal position and sucking my thumb.